Open-label study of donepezil in chronic poststroke aphasia.
نویسندگان
چکیده
une angiomatose diffuse cortico-méningée non calcificante et une démyélinisation progressive de la substance blanche. J Neurosurg 1946; 9:42–54. 6. Gururaj AK, Sztriha L, Johansen J, Nork M. Sturge-Weber syndrome without facial nevus: a case report and review of the literature. Acta Paediatr 2000;89:740–743. 7. Ward JB, Katz NN. Combined phakomatoses: a case report of SturgeWeber and Wyburn-Mason syndrome occurring in the same individual. Ann Ophthalmol 1983;15:1112–1116.
منابع مشابه
A randomized, placebo-controlled study of donepezil in poststroke aphasia.
We studied 26 patients in a randomized, placebo-controlled, double-blind parallel trial to evaluate the efficacy and safety of donepezil in chronic poststroke aphasia. Donepezil (10 mg/day) improved aphasia severity at endpoint (week 16) relative to placebo (p = 0.037).
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Donepezil (DP), a cognitive-enhancing drug targeting the cholinergic system, combined with massed sentence repetition training augmented and speeded up recovery of speech production deficits in patients with chronic conduction aphasia and extensive left hemisphere infarctions (Berthier et al., 2014). Nevertheless, a still unsettled question is whether such improvements correlate with restorativ...
متن کاملIn-Home Synchronous Telespeech Therapy to Improve Functional Communication in Chronic Poststroke Aphasia: Results from a Quasi-Experimental Study.
BACKGROUND Although the use of telepractice in speech-language therapy for assessment purposes is well documented, its effectiveness and potential for rehabilitation in poststroke aphasia remain largely unknown. The purpose of this study was to investigate the effectiveness of a remotely delivered synchronous pragmatic telespeech language therapy for improving functional communication in aphasi...
متن کاملOpen-label, multicenter, phase 3 extension study of the safety and efficacy of donepezil in patients with Alzheimer disease.
BACKGROUND Donepezil hydrochloride is a selective acetylcholinesterase inhibitor approved for the symptomatic treatment of mild to moderately severe Alzheimer disease (AD). Controlled clinical trials of up to 24 weeks have demonstrated that donepezil treatment (5 and 10 mg/d) significantly improves cognition and global function. OBJECTIVE To investigate the long-term benefits of donepezil tre...
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Anomia is a frequent and persistent symptom of poststroke aphasia, resulting from damage to areas of the brain involved in language production. Cortical neuroplasticity plays a significant role in language recovery following stroke and can be facilitated by behavioral speech and language therapy. Recent research suggests that complementing therapy with neurostimulation techniques may enhance fu...
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ورودعنوان ژورنال:
- Neurology
دوره 60 7 شماره
صفحات -
تاریخ انتشار 2003